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120世紀60年代[4]開始被用作常用麻醉劑，治療失眠、抑鬱症並用於提高運動成績。在義大利，γ-羥基丁酸以Alcove的商品名（ATC代碼N07BB）出售，γ-羥丁酸被用於治療酒精依賴（每天50至100毫克每公斤體重，分3次或更多次服用），包括迅速戒酒和短期到長期戒毒。
[編輯] 參考資料
- ^ Weil, Andrew; Winifred Rosen. Depressants. From Chocolate to Morphine. 2nd. Boston/New York: Houghton Mifflin Company. 1993: 77. ISBN 0-395-66079-3.
- ^ Erowid GHB Vault : Legal Status
- ^ Jazz Pharmaceuticals Inc (JAZZ.O) Full Description | Stocks | Reuters.com
- ^ 4.0 4.1 Theodore I Benzer. Toxicity, Gamma-Hydroxybutyrate. eMedicine. January 8, 2007.
- ^ Alexander Saytzeff. Über die Reduction des Succinylchlorids. Liebigs Annalen der Chemie. 1874, 171: 258–290. doi:10.1002/jlac.18741710216.
- ^ H. Laborit, J.M. Jouany, J. Gerald, F. Fabiani. Generalities concernant l』etude experimentale de l』emploi clinique du gamma hydroxybutyrate de Na. Aggressologie. 1960, 1: 407.
- ^ Wu Y, Ali S, Ahmadian G, et al.. Gamma-hydroxybutyric acid (GHB) and gamma-aminobutyric acidB receptor (GABABR) binding sites are distinctive from one another: molecular evidence. Neuropharmacology. December 2004, 47 (8): 1146–56. doi:10.1016/j.neuropharm.2004.08.019. PMID 15567424.
- ^ Cash, C. γ-hydroxybutyrate receptor function studied by the modulation of nitric oxide synthase activity in rat frontal cortex punches. Biochemical Pharmacology. 1999, 58: 1815. doi:10.1016/S0006-2952(99)00265-8.
- ^ 9.0 9.1 9.2 Maitre M, Humbert JP, Kemmel V, Aunis D, Andriamampandry C. [A mechanism for gamma-hydroxybutyrate (GHB) as a drug and a substance of abuse]. Med Sci (Paris). March 2005, 21 (3): 284–9. PMID 15745703 (French).
- ^ Waszkielewicz A, Bojarski J. Gamma-hydrobutyric acid (GHB) and its chemical modifications: a review of the GHBergic system (PDF). Pol J Pharmacol. 2004, 56 (1): 43–9. PMID 15047976.
[編輯] 外部連結